Chromium Picolinate is a nutritional supplement that works to increase the efficiency of insulin to optimal levels. This popular nutritional supplement is a combination of the element chromium and picolinic acid. FDA recommends a daily chromium intake of approximately 130 mcg, as small amounts of chromium are needed to aid the transport of blood glucose across cell membranes. Combining chromium with picolinic acid aids in chromium absorption. This version is the first release on CNET Download.com.