In today's evidence-based Medicine an intimate knowledge of the trials is mandatory. However, the sheer number of studies, especially in Cardiology makes the orientation very difficult for the non-cardiologist. Therefore, this reference will be very useful for residents of all disciplines, family doctors as well as for any other interested health professionals. The selected 25 trials changed practice in Cardiology and the authors also put them into perspective, explaining why these studies were so important and how they influenced current practice.
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